Dynamic DNA methylation reprogramming: Active demethylation and immediate remethylation in the male pronucleus of bovine zygotes
نویسندگان
چکیده
منابع مشابه
Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes.
In mammalian zygotes, the 5-methyl-cytosine (5mC) content of paternal chromosomes is rapidly changed by a yet unknown but presumably active enzymatic mechanism. Here, we describe the developmental dynamics and parental asymmetries of DNA methylation in relation to the presence of DNA strand breaks, DNA repair markers and a precise timing of zygotic DNA replication. The analysis shows that disti...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2007
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.21278